Modeling Synaptic Plasticity in the Basal Ganglia

Deep Brain Stimulation (DBS) of the Basal Ganglia (BG) is a common treatment for Parkinson's Disease (PD), and other neurological disorders. When DBS therapy is applied, different symptoms have different wash-out times, some symptoms cease immediately and others take minutes to hours to fully abate. This project will focus on incorporating synaptic plasticity into network models of DBS in the BG to try to explain this phenomenom.

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